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Study finds correlation between high-fat Western diet and pain
Advanced Back and Neck Care • June 26, 2021

The Western diet is associated with many ills, and now chronic pain may be added to the list.

Fats provide important health benefits, but they can be too much of a good thing. Most people eat too many omega-6 fats and not enough omega-3. A new study looks at the potential for omega-6 fats’ influence on neuropathic pain in people with diabetes and other conditions.

Researchers at the University of Texas Health Science Center at San Antonio studied the effects of omega-6 fatty acids themselves by measuring the role of these dietary lipids in pain conditions and found that the substances themselves seem to cause pain and inflammation.

The abundance of omega-6 polyunsaturated fats prominent in the typical Western diet “served as a significant risk factor for both inflammatory and neuropathic pain,” UT said in a statement.

Diabetes, autoimmune disorders and cardiovascular diseases are known to be affected by nutritional choices, the researchers said. But excessive consumption of omega-6 fats, which are found largely in commonly consumed processed foods, had not been studied in terms of the acids themselves and their role specifically in pain.

A team from the biomedical sciences, the department of chemistry and the neurology department at the South Texas Veterans Health Care System headed by Dr. Jacob Boyd studied polyunsaturated fatty acids in both mice and humans.

While both omega-6 and omega-3 fats are essential for proper nutritional health, the new study suggests that the preponderance of the former could have detrimental effects. The five-year study was published in the June edition of the journal Nature Metabolism.

Omega-6 fats mainly occur in foods with vegetable oils and are beneficial – to a point.

“But Western diets associated with obesity are characterized by much-higher levels of those acids in foods from corn chips to onion rings, than healthy omega-3 fats, which are found in fish and sources like flaxseed and walnuts,” the researchers’ statement said. “Generally, unhealthy foods high in omega-6 fats include processed snacks, fast foods, cakes, and fatty and cured meats, among others.”

Reversing those dietary habits and increasing omega-3 fats “greatly reduced these pain conditions,” the researchers found. “Also, the authors demonstrated that skin levels of omega-6 lipids in patients with Type 2 diabetic neuropathic pain were strongly associated with reported pain levels and the need for taking analgesic drugs.”

While more research needs to be done, the work could lay a “foundation for new clinical trials and ultimately provide new avenues for the clinical treatment of neuropathies,” wrote Duke University researchers Aidan McGinnis and Ru-Rong Ji.

By THERESA BRAINE
NEW YORK DAILY NEWS

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Originally posted on January 30,2023, this article has been updated on August 24, 2024 to reflect the latest research and statistics. Our editorial team has ensured you’re viewing the most current data on this topic. Need help or have a question? Email us.
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Ronald Grisanti D.C., D.A.B.C.O., DACBN, MS, CFMPXylitol and Erythritol are commonly used by those wanting to lose weight or who are diabetic. Many people use artificial, low-calorie sweeteners to reduce their sugar intake. It's found in chewing gum, toothpaste, sugar-free candy, baked goods, and more. According to a June 2024 study, high levels of xylitol and erythritol, sugar alcohols and low-calorie sweeteners used in many foods and products, has been associated with an increased risk of a major cardiovascular event, like a heart attack or stroke and death. The researchers in this study analyzed how xylitol impacts heart health in over 3,000 patients in the U.S. and Europe. The team of researchers, led by Dr. Stanley Hazen at the Cleveland Clinic and published in European Heart Journal on June 6, 2024 showed that having the highest blood levels of xylitol is linked with a 57% increased risk of a major cardiovascular event compared with lower levels. The Reason Why Xylitol and Erythritol May Pose a Cardiovascular Risk? Blood components called platelets help blood to clot. The researchers found that both erythritol and xylitol made platelets more sensitive to blood clotting signals. . Additionally, taking a single 30-gram dose of xylitol increases blood levels 1000-fold within 30 minutes – this increase can stimulate blood clotting, which is concerning for people with existing heart disease. These results suggest that consuming erythritol and xylitol can increase blood clot formation. This, in turn, could increase the risk of heart attack or stroke. What Products Commonly Include Erythritol and Xylitol? Chewing gum Candy Ice Cream Breath mints Some Dietary supplements Mouthwash Toothpaste Sugar-Free Desserts Liquid compounded medications Commercially produced: Baked goods, beverages, candies, chewing gums, chocolates, tabletop sweetener packets, ice cream, puddings, jams and jellies, fruit preparations, biscuits, and sauces Dr. Grisanti's Comments For now, I recommend being cautious using products with xylitol and erythritol in it, – particularly those with cardiovascular risk factors. Although some people will say the research may be flawed, I have to wonder if the people against this new study have an agenda that places the public at risk. All in all, I say why take the risk. I prefer to err on the side of caution and simply stop consuming food items that have erythritol and xylitol in it. Using xylitol and erythritol in the small amounts typically found in chewing gum, toothpastes, and mouth rinses seems to be safe. But using it in very high doses and long-term isn't a good idea. It does not mean throw out your toothpaste if it has xylitol in it, but we should be aware that consumption of a product containing high levels could increase the risk of blood clot-related events. If you're looking for a sweet treat, the only sweeteners I stand behind are organic, 100 percent stevia or monk fruit extracts. Remember simply read the labels of the items you eat or drink if you want to know if xylitol and erythritol has been added. --------- ATTENTION DOCTORS, ALL HEALTHCARE PRACTITIONERS, PATIENTS and POTENTIAL NEW PATIENTS If you found this article of value may I ask if you can tell your friends and colleagues about Clinical Rounds. This is a great introduction to the field of functional medicine as well as having the opportunity to stay current on the latest medical news on a variety of important health issues. Here is the webpage to subscribe: http://www.clinicalrounds.com References: https://www.nih.gov/news-events/nih-research-matters/xylitol-may-affect-cardiovascular-health https://www.nbcnews.com/health/heart-health/xylitol-linked-increased-heart-risk-reconsider-sugar-substitutes-rcna155688 https://www.nhlbi.nih.gov/news/2024/common-sweetener-linked-potential-cardiovascular-risks https://academic.oup.com/eurheartj/article/45/27/2439/7683453 https://www.washingtonpost.com/wellness/2024/06/06/xylitol-sugar-artificial-sweetener-heart/ https://www.nih.gov/news-events/nih-research-matters/erythritol-cardiovascular-events https://www.nature.com/articles/s41591-023-02223-9 https://academic.oup.com/eurheartj/article/45/27/2439/7683453 https://academic.oup.com/eurheartj/article/45/27/2439/7683453 ** Always consult with a physician or healthcare practitioner with significant integrative or functional medicine training before starting any of the above recommendations. You can find a qualified and certified functional medicine practitioner by going to: www.FunctionalMedicineDoctors.com The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Grisanti and his functional medicine community. Dr. Grisanti encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional. Visit www.FunctionalMedicineUniversity.com for more information on our training in functional medicine. Look for practitioners who have successfully completed the Functional Medicine University's Certification Program (CFMP) www.functionalmedicinedoctors.com . This content may be copied in full, with copyright, contact, creation and information intact, without specific permission, when used only in a not-for-profit format. If any other use is desired, permission in writing from Dr. Grisanti is required
May 1, 2024
https://www.functionalmedicineuniversity.com/public/2017.cfm ** Feel free to use this article on your website. and have it linked back to www.FunctionalMedicineUniversity.com ** Read my past articles: http://www.functionalmedicineuniversity.com/public/department88.cfm ATTENTION DOCTORS AND ALL HEALTHCARE PRACTITIONERS Tell your friends and colleagues about Clinical Rounds . This is a great introduction to the field of functional medicine. Here is the webpage to subscribe: http://www.clinicalrounds.com Take care, Ron P.S. Please visit our facebook page and "Like It" Of course if you really like it. :) http://www.facebook.com/pages/Functional-Medicine-University/161486170671332
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https://www.functionalmedicineuniversity.com/public/2012.cfm ** Feel free to use this article on your website. Compliments from Functional Medicine University . ** Read my past articles: http://www.functionalmedicineuniversity.com/public/department88.cfm View Rick Bramos Fitness YouTube Channel https://www.youtube.com/channel/UC_x4I27Z0DfYkfcroXxAhcA/videos Here is Rick's New Video of the Week: https://youtu.be/Pk9FeTKlufU Rick is now offering phone consultations for those wanting to lose weight or simply to improve their fitness. Rick can be reached at 2days2fitness@gmail.com for more details. ATTENTION DOCTORS AND ALL HEALTHCARE PRACTITIONERS Tell your friends and colleagues about Clinical Rounds . This is a great introduction to the field of functional medicine. Here is the webpage to subscribe: http://www.clinicalrounds.com Take care, Ron P.S. Please visit our facebook page and "Like It" Of course if you really like it. :) http://www.facebook.com/pages/Functional-Medicine-University/161486170671332
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https://www.functionalmedicineuniversity.com/public/2006.cfm ** Feel free to use this article on your website. All I ask is to add at the bottom of the article: Compliments from Functional Medicine University and have it linked back to www.FunctionalMedicineUniversity.com ** Read my past articles: http://www.functionalmedicineuniversity.com/public/department88.cfm ===================== View Rick Bramos Fitness YouTube Channel https://www.youtube.com/channel/UC_x4I27Z0DfYkfcroXxAhcA/videos Here is Rick's New Video of the Week: https://youtu.be/Pk9FeTKlufU Rick is now offering phone consultations for those wanting to lose weight or simply to improve their fitness. Rick can be reached at 2days2fitness@gmail.com for more details. ===================== ATTENTION DOCTORS AND ALL HEALTHCARE PRACTITIONERS Tell your friends and colleagues about Clinical Rounds . This is a great introduction to the field of functional medicine. Here is the webpage to subscribe: http://www.clinicalrounds.com Take care, Ron P.S. Please visit our facebook page and "Like It" Of course if you really like it. :) http://www.facebook.com/pages/Functional-Medicine-University/161486170671332
By Ronald Grisanti D.C., D.A.B.C.O., DACBN, MS, CFMP March 13, 2024
https://www.functionalmedicineuniversity.com/public/2000.cfm ** Feel free to use this article on your website. Compliments from Functional Medicine University . ** Read my past articles: http://www.functionalmedicineuniversity.com/public/department88.cfm ===================== View Rick Bramos Fitness YouTube Channel https://www.youtube.com/channel/UC_x4I27Z0DfYkfcroXxAhcA/videos Here is Rick's New Video of the Week: https://www.youtube.com/watch?v=W__EwtXJkyY Rick is now offering phone consultations for those wanting to lose weight or simply to improve their fitness. Rick can be reached at 2days2fitness@gmail.com for more details. ===================== ATTENTION DOCTORS AND ALL HEALTHCARE PRACTITIONERS Tell your friends and colleagues about Clinical Rounds. This is a great introduction to the field of functional medicine. Here is the webpage to subscribe: http://www.clinicalrounds.com Take care, Ron P.S. Please visit our facebook page and "Like It" Of course if you really like it. :) http://www.facebook.com/pages/Functional-Medicine-University/161486170671332
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